SYRUP 200 ML

MECHANISM OF ACTION

NSAIDs, a derivative of phenylpropionic acid, ibuprofen has anti-inflammatory, analgesic and antipyretic effects.
The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever.

THERAPEUTIC INDICATIONS

Trifen Syrup belongs to a group of medicines called anti-inflammatory painkillers. It can be used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis (including juvenile rheumatoid arthritis or Still's disease), arthritis of the spine, ankylosing spondylitis, swollen joints, frozen shoulder, bursitis, tendinitis, tenosynovitis, lower back pain, sprains and strains.
Trifen Syrup can also be used to treat other painful conditions such as toothache, pain after operations, period pain and headache, including migraine. It can also be used for the short term treatment of fever in children over the age of 1 year.
 Each 5ml spoonful of Trifene Syrup contains 100mg ibuprofen.

DOSING AND ADMINISTRATION

Children - TRIFENE Syrup should NOT be taken by children weighing less than 7 kg. When used to treat fever, the syrup should not be used in the long term or given to children under the age of 1 year

The usual dose in children is 20 mg per kg of bodyweight each day, in divided doses. This can be given as follows:

• 1-2 years: One 2.5 ml (50 mg) dose three/four times a day
• 3-7 years: One 5 ml (100 mg) dose three/four times a day
• 8-12 years: Two 5 ml (200 mg) doses three/four times a day